An even more complex visualization of a 2D hierarchical clustering is shown in Fig. 5f, in which genes are clustered based on their expression patterns across several conditions (vertical tree on the left) and conditions are clustered across genes (horizontal tree).
While in early days chemical intuition and simple statistics (structure activity relationship – SAR) were leading the drug design process, in later days more complex statistics and visualization tools have become routinely part of quantitative structure activity relationship (QSAR) studies.
Overall, Sequence is a solid contribution to web-based visualization that is useful as it is and forms the foundation for more complex web-based sequence visualization in the future.
On modern computers, the frame rate of even very complex visualizations is more then sufficient to show a smooth animation; and iii) Interpolation of the images by gradually blending them (fade in and out).
The definition of such attributes is important as they can be tied to actionable processes, such as analyses, visualizations, and ultimately more complex workflows.
Further work should be done by taking multiple factors into consideration, such as more complex geological objects, comprehensive modeling, manipulation methods, and visualization.
