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The proposed methodology can be used as a tool to solve more complex variants of this class of problems as well as other discrete location and network design problems involving servicing decisions.
The production of new, more complex, variants on well-studied models in biology can often aid in two ways.
Alignment yield increased when programs were allowed to identify more complex variants.
Specifically, support for both intra- and inter-chromosomal translocations will be added, as well as support for moderate-sized insertions and more complex variants consisting of overlapping SVs.
In common with many laboratories, we perform automated variant annotation using both alamut-HT (Interactive Biosoftware, Rouen, France) to annotate single-nucleotide changes or small indels and Pindel [ Ye et al., 2009] for more complex variants.
The precise localization of the boundaries of structural variants provided by the GASV is helpful for distinguishing simple variants shared across multiple individuals from more complex variants resulting from repeated rearrangements at the same locus.
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I don't see a single reason why somebody who invented the whole story would ever get into a more complex variant of a surgical intervention.
A slightly more complex variant is taking the dot product of the two spectra, taking into account peak intensities.
Therefore it could be expected that inhibition of the appropriate muscarinic acetylcholine receptors could lead to decreased production of phospholipase C and hence phospholipidosis by a more complex variant of mechanism 1.
This development was aided by the modular nature of many signal transduction proteins, which is particularly notable in the dominant type of prokaryotic signal transduction network, the 'two-component regulatory system', including its more complex variant, the 'phosphorelay system' (Nixon et al. 1986; Burbulys et al. 1991).
Also, the more complex variant of the two-component system, known as the phosphor-relay system comprised of an autophosphorylatable hybrid HK, one or more histidine phosphotransferases (HPT) and a terminal RR was totally absent, because no HPT domains were found in these strains.
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more complex interpretations
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