Sentence examples for more complex sphingolipids from inspiring English sources

Ceramides are the "simplest" of the sphingolipids, in that they only contain hydrogen as the head group, and they serve as a template for the synthesis of more complex sphingolipids.

However, no further steps involving the recycling of ceramides and other more complex sphingolipids (such as the SM catabolic pathway and salvage pathway) are considered.

The major disaccharide (Galβ1 4Glcβ1-ceramide), lactosylceramide (LacCer), is a critical intermediate in the biosynthesis of all of the root structure families of more complex sphinGalβ1 4Glcβ1-ceramide

Plants also synthesize ceramide and more complex sphingolipids, some of which have been localized to detergent-resistant membrane domains [ 30- 32].

There is also evidence that Orm1 and Orm2, when phosphorylated at unique sites by protein kinase Npr1, promotes steps in the sphingolipid pathway that lead to more complex sphingolipids (Shimobayashi et al., 2013).

Two of these newly identified Ypk1 target proteins form part of an enzyme complex called ceramide synthase, which produces a family of waxy lipid molecules from which more complex sphingolipids are built.

This growth-promoting function of d17iso-SPA may be mediated by a more complex sphingolipid derived from it.

Mammalian sphingolipids are more complex, with sphingomyelin being the major sphingolipid, in addition to various classes of saturated and unsaturated ceramides [32,33].

The major functions of the desaturases and hydroxylases in this system are to catalyse double bond formation between carbon atoms and addition of hydroxyl groups during the biosynthesis of unsaturated fatty acids (UFAs) and the more complex lipids the sphingolipids and sterols (Huang et al., 1999; Knutzon et al., 1998; Michaelson et al., 2013; Grinstead and Gaylor, 1982; Moreno-Perez et al., 2011).

Because it is technically difficult to purify or synthesize sphingolipids of more complex structure (e.g., glucosylceramide [GlcCer]) and directly test their effect by dietary supplementation, we examined additional enzymes involved in sphingolipid synthesis.

The situation appears to be more complex as various trafficking pathways regulate sphingolipid acquisition [ 99, 106].