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Other more complex scoring systems have greater prognostic accuracy but ASA scoring remains useful [ 10].
The use of more complex scoring systems added little to the prognostic performance.
The use of the more complex scoring systems APACHE II, SAPS II and SOFA added little to the prognostic performance.
The ACQ and the ACT have more complex scoring systems not easily deconstructed and replicated for this analysis [ 30, 33- 35].
From a genetics perspective, our model is a more complex scoring function for the identification of a single, causative gene instead of the conventional multi-gene QTL interval.
Nevertheless, this is a very useful web resource for the intensive care clinician or researcher, and is a valuable aid that facilitates utilization of the more complex scoring systems.
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To date, more complex scores generated by logistic regression analysis (Olmos et al, 2012) have not outperformed the RMS.
Furthermore, the NACA score has a limited correlation to more complex patient scoring systems, 2 such as the Injury Severity Score, 14 but the NACA scoring's simplicity may explain a far more widespread application in pre-hospital health care than more complex scores, which often rely on data known only after many hours in hospital.
However the LA-classification, evaluating the extent of mucosal breaks in a short segment, is quite different from the more complex score of diffuse mucosal inflammation in UC characterised by at least 4 different endoscopic features.
Also, rather than using the NMS, the prefracture functional level in previous studies was evaluated with more complex scores such as the Katz score (Soderqvist et al. 2006), the Functional Independency measure (Cornwall et al. 2004), and the Functional Recovery score (Zuckerman et al. 2000).
33 In this study, the AST ALT ratio provided the best negative predictive value for advanced fibrosis and also demonstrated good diagnostic accuracy with a C statistic of 0.83 which was comparable to or better than results for more complex scores, where C statistics ranged from 0.67 to 0.86.
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