Sentence examples for more complex pedigrees from inspiring English sources

In more complex pedigrees, the transmission probability should not be conditioned only on parents phases and progeny marker phanotypes.

As such, the model efficiently approximates more complex pedigrees for which exact computation of IBD status is intractable.

Improvements in breeding and selection of shrub willow through the development of more complex pedigrees, compared to those in previous years, has potential to increase yield productions.

The proposed method can also be generalized to IBD tracing in more complex pedigrees, i.e., beyond a single generation, allowing information from various types of relatives to be exploited by linkage analysis e.g., [ 13].

We believe that the fact that more complex pedigrees contain more information on the co-inheritance of rare risk variants in association with disease status accounts for much of our proposed method's increased power to detect rare causal variants.

For simplicity, we will describe the algorithm in terms of the affected siblings of unrelated parents, but note that the algorithm is equally applicable to more complex pedigrees in which multiple affected relatives share the same two disease haplotypes, as well as to pedigrees of consanguineous unions in which affected persons share two haplotypes that are identical by descent.

Prior to collecting data on phenotypes, the sampling variance can be predicted using statistical theory, typically for balanced designs, or obtained from computer simulation for more complex pedigree structures.

Each pedigree included only one proband: 90 families, thirty-four pedincludedncluded 1st degree relatives (parents and sibs of the proband), fifty-six pedigrees had a more complex structure they included 2nd and 3rd degrees relatives (grandmothers, grandfathers, aunts, uncles, and cousins).

90 families, thirty-four pedincludedncluded 1st degree relatives (parents and sibs of the proband), fifty-six pedigrees had a more complex structure they included 2nd and 3rd degrees relatives (grandmothers, grandfathers, aunts, uncles, and cousins).

The goal was to draw close connections from such fundamental concepts as Mendelian inheritance and pedigrees to the more complex topics of phylogenetics and tree thinking.

In the latter group, the hypomethylation is isolated to TNDM1 DMR in 41% (4) (12 of 29 pedigrees, Fig. 3) or part of a more complex hypomethylation, TNDM1 HIL, in 59% (4) (17 of 29 pedigrees).