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Recently, Kohane stated that "the size and complexity of needed multidimensional characterization of patients will lead to far more complex diagnostic and prognostic categories than are currently in use" [ 1].
However, improving diagnosis to one disease may lead to over diagnosis of another illness, in this case urinary tract infections; highlighting the need for ever more complex diagnostic and health services.
Further, physicians avoid requesting the more complex diagnostic tests required for adults such as the RT-PCR (reverse transcription polymerase chain reaction) and/or blood tests [ 22, 50].
The aetiological diagnosis of stroke in young adults needs a different and more complex diagnostic work up than in older adults.
As F-FDG PET/CT will be more frequently used as a screening tool in more complex diagnostic settings like fever and inflammation of unknown origin, a routine investigator-independent strategy for establishing the diagnosis of LVV is needed.
The need for more complex diagnostic subclassification of NHL has increased as the role of treatments specific to particular entities has emerged, for example, diffuse large B-cell lymphoma must be rapidly distinguished from Burkitt lymphoma to achieve the optimum outcome in both types.
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Pathological evaluation of breast specimens has shifted rapidly from a mere diagnostic process, aimed at establishing the biological potential of a breast 'lump', to a far more complex integration of diagnostic, prognostic and predictive parameters.
Moreover, the need to use more complex and costly diagnostic methods, especially when the sputum smear is negative, may imply a delay in the diagnosis of TB, as reported in a previous study [ 6].
Use more complex and technical diagnostic methods.
They also looked for evidence that ultrasound use could reduce the need to carry out other more complex and more expensive diagnostic tests.
Acute cough may be more complex and have more diagnostic uncertainty than guidelines and performance measures presume.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com