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Exact(7)
Invasive coronary angiography should be reserved for patients with more complex coronary lesions or for therapeutic measures.
However, patients enrolled in these randomized clinical trials represent a select group, and the efficacy of VBT in patients with ISR who were excluded from these controlled trials due to more complex coronary anatomy requires further investigation.
7 8 A poor outcome in the elderly population may be associated with more complex coronary disease, increased comorbidity and higher risk of complication from revascularisation procedures.
A number of reasons may explain the worse outcomes associated with CKD, including more complex coronary anatomy, a greater atherosclerotic burden, an underlying prothrombotic state, and decrease platelet responsiveness to antiplatelet agents in the setting of CKD [ 19- 25].
Multiple reasons likely underlie the marked association between severe CKD and poor outcomes, including a greater number of cardiovascular risk factors, more complex coronary anatomy, increased overall atherosclerotic disease burden, and lower frequency of PCI and other recommended ACS treatments during hospitalization and follow up in patients with CKD [ 26- 28].
Patients with low or intermediate SYNTAX scores in the CABG and in the PCI group had similar rates of major adverse cardiac or cerebrovascular events, whereas among patients with high scores (indicating more complex coronary anatomy), the event rate was significantly increased in the PCI group.
Similar(53)
But the author stated that the CABG group had more patients with complex coronary lesions which could be responsible for such an outcome.
A higher incidence of multivessel disease, more complex lesions, and poor coronary blood flow before and after PCI may contribute to the poor results of reperfusion therapy.
Newer stents are manufactured by altering basic design characteristics to tackle complex coronary morphologies more effectively.
The number of involved vessels did not differ among the groups; patients with severe RD had more complex lesions in the left main coronary artery and in the infarct-related artery compared with the mild renal dysfunction group.
Compared with younger patients, elderly patients who undergo coronary angiography (CAG) present more complex lesions, higher comorbidity, poorer clinical outcomes and higher mortality [ 2, 3].
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com