The analysis of more complex multi-compartment neuron models under HFS will be the subject of future research.
The different sampling frequency used to gather data in the i.v. study enables a more complex three-compartment model to be assigned.
As a consequence thereof, the experimental test design needs to reflect this: the more complex the tested compartment, tier 2 considers experimental setups stronger mimicking the representative environmental compartment [45].
However, in the more complex situation of compartment formation in many living organisms, it is not yet entirely clear to what extend differential adhesion applies [ 554, 603] and how other complementary mechanisms help to establish stable compartment boundaries or to orchestrate tissue dynamics over time (see [ 554]).
On the other hand, a multicompartment model, e.g., the physiologically based toxicokinetic (PBTK) model developed for fish by Nichols and co-workers, may be viewed as more complex than one-compartment models because it requires more physiological data and simulates multiple compartments.
A similar rerouting (though visually much more complex, due to intracellular compartments) can be observed for Design 5, based on yeast (Additional file 1: Figure S7).
More complex designs include a laptop compartment that unzips and can be folded down flat on the belt.
However, in more complex fractures, the risk of compartment syndrome is considerably higher.
Our hypothesis is that the luminal cell compartment is more complex than initially described, and that an understanding of the developmental relationships within this lineage will help in understanding the cellular context in which breast tumours occur.
This relay system transforms a pattern of binary expression (Hh on in the posterior compartment, off in the anterior compartment) to the more complex nested patterns of expression of Dpp target genes.
