23 This result could indicate that the Danish Leukemia Registry is more complete than other registries.
The estimated incidence may indicate that the DNLR truly is more complete than other registries.
These local registries are more complete than the regional cancer registries, as clinics sometimes wait for histologic confirmation before sending notification of cases to the regional cancer registry, and the delay between the first acoustic neuroma diagnosis and a subsequent diagnostic surgical procedure can be substantial.
8 10–12 Parallel results from multiple large registries, including a more complete follow-up from the Swedish registry, have also indicated no increase in mortality for DES compared with BMS.
These data were generally more complete than most cancer registries would allow.
More complete ascertainment by cancer registries has also been proposed (Adamson et al, 2005), and while this may have had some impact in the early 1970s, under-ascertainment of childhood cancers has been estimated at less than 5% during 1971 1984 (Hawkins and Swerdlow, 1992).
If only one source was to be used, then in England and Wales, cancer registry would be more complete with only 6.8% of women with BC missed/misclassified compared with 15.6% using self-reported data alone.
Partly this requires increased support to cancer registries to provide more complete data on the current and future scale of the disease at a country and regional level.
In general the estimation of risk varies, between hospital based and population based studies [ 2], probably due to more complete follow-up in the former registries.
Current efforts to link registry data with administrative claims suggest that, while data on ambulatory treatment is still underreported in cancer registries, it is more complete in contemporary data than in earlier studies.
