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At present, it remains unclear whether ossicle tissue would tolerate relevant increases of pressure to levels that might allow for a more complete eradication of microbial agents.
It is quite plausible that lower plasma E2 levels afforded by letrozole treatment provide for more complete eradication of micrometastatic tumor deposits, which could in turn result in fewer DM recurrences.
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Prevention would be more realistic and practicable than complete eradication.
Further investigation of these mechanisms, for example, through RNA macro-array analysis, might open new avenues for novel therapeutic strategies aimed at broader and more ambitious targets, such as complete eradication of lentiviral infections.
For the complete eradication of GBS, more than one molecular strategy is necessary in a given patient.
30, 32 With deeper lesions (compound and dermal nevus), complete eradication is much more difficult, and recurrence is common.
At the same concentration, HAMLET reduced the viability of S. pneumoniae by more than 6 log10 within 1 hour, with complete eradication of the inoculum (8 lobtainedtatned at 250 µg/ml (Fig. 1A).
Complete eradication of poliovirus is, however, more difficult than what has been initially anticipated, because of persistence of wild type poliovirus transmission and recurring outbreaks in polio-free countries (reviewed by Wassilak et al).
Since 1988, vaccination has reduced polio by more than 99% worldwide, and the disease is slated for complete eradication.
Consensus reached: 100% agreement While a proportion of recurrent/residual polyp tissue can be successfully treated with repeat snare resection, complete eradication at repeat therapy may be much more difficult to achieve, such as with larger areas of recurrence.
Therapeutic options that provide a complete eradication of HSV-2 including suppression of genital inflammation may be more relevant for decreasing HIV transmission in high HSV-2 prevalent regions.
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