As both the practice and the terminology become more common, variations emerge.
Amongst the more common variations of R 2 is the adjusted R 2, R 2 adj, which adjusts for the number of variables in the regression equation.
In contrast with these very rare, gene-specific mutations, more common variations in genes (polymorphisms) might cause more subtle variations in DNA repair capacity at the population level, in particular when multiple genes from one pathway are studied [ 109].
Partial or complete albinism is known in some species, but a more common colour variation is ambicoloration (coloration on both sides).
The potential role of the coding and non-coding BRIP1 SNPs identified in this report remains unclear, as it is possible that a more common genetic variation contributes to PCa risk.
More explicitly, common variation within several genes is thought to confer enhanced susceptibility towards the aforementioned environmental challenges [1].
Thus, it appears that the 5' end polymorphism confined to a few miRNAs is a result of Drosha processing shift while the more common 3'end variations observed in most miRNAs is due to modifications introduced after the Drosha/Dicer processing.
It is possible that the chromosome 17 linkage observed in multiplex PCGP families is because of mutations in a nearby gene, and the more common BRIP1 variations observed by us and others may have more subtle influences on disease susceptibility.
Copy number variation in the DEFA1A3 region is reported to be much more common than the variation identified by Redon et al [ 22].
This is consistent with the general observation that 3'-end sequence variation is more common than 5'-end variation [ 20, 32, 34, 39].
