Sentence examples for more common mutations from inspiring English sources

Another LC ePatient suggested that because she was young (55), healthy, never smoker with adenocarcinoma, and tested negative for the more common mutations, she fit the profile of patients who had a new mutation called ROS1.

Vertex shares have fallen 37% from their high earlier this year because of doubts by investors that Vertex will succeed in its attempts to dramatically expand Kalydeco's use by combining it with a second drug that will make it work in CF patients whose disease is caused by other, more common, mutations.

Among this group of disorders, one of the more common mutations is in hepatocyte nuclear factor 1 homeobox B (HNF1B).

Our simulations show that for low compression levels (d=2, 3) there is hardly any loss of P suc even for more common mutations.

As pointed out by Kimura (1983), however, Fisher neglected the fact that, among beneficial mutations, the few mutations with large effect have a higher fixation probability than the more common mutations with small effects.

Several of the more common mutations have been previously reported to be associated with cardiovascular disease, such as 10398A > G, which is associated with end-stage renal disease in African Americans with HTN [ 34].

Despite the more common mutation of p53 in HPV negative cases, a substantial number of vulval SCC occur which lack both mutation and HPV.

The potentiator, VX-770, known as Ivacaftor or Kalydeco, did not exhibit similar efficacy in patients homozygous for the more common mutation, ΔF508, however.

The more common mutation from KG to NSTN, the other removes a stop-codon changing the last 13 AA and adding 40 new AA (STQNAEFFCHWFSILSAAFWCVLDFWRLSDPTGG AGIPLFRPGHRGDRLKKTG).

Mutations in two different genes (hemojuvelin and hepcidin) have been shown to cause two forms of juvenile HH. 14 The more common mutation occurs in the hemojuvelin (HJV) gene on chromosome 1q.

Moreover, it might be that loss of function of CDKN1C is a more common mutation than currently realised, for example, in cases of cleft palate or abdominal wall defects in the absence of fetal overgrowth and in cases in which the mother develops preeclampsia.