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Maybe it's an unusual disease, known best by specialists, or perhaps it's an unusual presentation of a more common illness.
Depression is a much more common illness than mania, and there are indeed many sufferers from depression who have never experienced mania.
While Ms. Roberts may have brought attention to a rare disease -- and donations from CNN and C-Span viewers who might not have otherwise heard of Rett syndrome -- the money might have been better directed to a more common illness, Mr. Stier said.
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What about more common illnesses?
But finding genetic causes in more common illnesses caused by many genes interacting has been far harder.
Lyme disease spreads to humans by infected ticks and symptoms include tiredness, muscle pain and headaches, meaning it can be mistaken for more common illnesses.
He said: "Other much more common illnesses than Ebola (such as flu, typhoid fever and malaria) have similar symptoms in the early stages, so proper medical assessment is really important.
Pneumococcus is a leading cause of pneumonia, meningitis, and more common illnesses like ear infections.
This is a much different model than Big Pharma which usually focuses on more common illnesses where the research ROI stands to be much greater.
Other patients often wait to seek proper treatment because some of the initial symptoms resemble those associated with more common illnesses.
Previous research has shown that loneliness is associated with negative health outcomes in chronic diseases such as cancer and heart disease, but nobody had looked at whether it also played a role in the outcomes of more common illnesses like the cold — until now.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com