Sentence examples for more closely recapitulate from inspiring English sources

Thus by targeting multiple cancer associated human mutations to the appropriate murine epithelia, mice develop tumours that more closely recapitulate the human disease.

These innovative systems often combine different cell populations in 3D environments that more closely recapitulate the different niches that exist within the developing or adult CNS.

To fully mobilize the cell's biological potential, a new generation of tissue engineering systems is now being developed to more closely recapitulate the native developmental milieu, and mimic the physiologic mechanisms of transport and signaling.

We show a method that can allow one to more closely recapitulate this microenvironment in 2D cell culture, which could be applied to any type of cell culture assay.

Other models that more closely recapitulate the sprouting angiogenic response have therefore been established.

Thus, by including additional features of local circuits in layer 2 of the MEC, E-I-I models may more closely recapitulate experimental observations.

Nevertheless, given that the effects of prenatal radiation often emerge later in life, our study more closely recapitulates what is encountered in clinical setting.

This model more closely recapitulates human colorectal cancer progression, in particular the spontaneous metastatic process that is highly dependent on the host environment [ 41].

While low doses of 15 25 mg/kg STZ induced a type 2 diabetic phenotype, higher doses more closely recapitulated type 1 diabetes, demonstrating that the severity of diabetes can be modified according to the requirements of the study.

Organoids closely recapitulate several properties of the original tumor.

Patient-derived xenograft (PDX) tumor models have been shown to closely recapitulate human tumor biology and predict patient drug response.