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Studies of the effects of mixtures of multiple salts present in produced waters and more chronic effect studies would give a better picture of the overall potential toxicity of these ions.
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More chronic effects, although prolonged, are only seen downstream of SSTW.
Beyond the acute heat stress, more chronic effects on the heart and kidneys may develop after repeated excessive body heating or dehydration (7).
Observational studies already consider some temporal patterns of health outcomes; for example, daily concentrations (or < 24 hr) are necessary for assessing acute effects and long-term concentrations (including seasonal variation) are required for assessing more chronic effects.
It is indeed important for clinicians treating patients with TC, to appreciate the acute as well as the more chronic vascular effects of cisplatin-based chemotherapy.
The kidney seems more sensitive to the chronic effect of cadmium than the lung.
When the treatment target (like the JIMT-1 cell line) is not fully sensitive to T-DM1, mitotic catastrophe develops as a more chronic and mild late effect.
Thus, in the absence of adequately designed studies, it may become increasingly challenging to differentiate substance-specific deposition-related acute effects from the more chronic retained cumulative dose-related effects.
Patients with more chronic diseases reported greater continuity (effect size = .70%).
In contrast more studies on chronic effects have elucidated disease-related processes, such as DNA damage, lung parenchyma destruction, increased plaque volume in arteries, lung fibrosis, or granuloma formation.
Although we attempted to remove the effect of acute glycemia on insulin sensitivity and the renal measures as much as possible, we cannot completely rule out the confounding effects of more chronic glucose toxicity.
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CEO of Professional Science Editing for Scientists @ prosciediting.com