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BP-II patietns had a substantially more chronic course, with significantly more major and minor depressive episodes and shorter inter-episode well intervals.
The patients having interictal pain have a more chronic course (69.0 vs 10.7 months, p = 0.0006).
Indeed, several DTNBP1 risk SNPs are significantly more common in the subset of schizophrenia cases marked not only by earlier adult onset and more chronic course, but by more prominent positive and negative symptoms, as well as greater cognitive deficits [15].
Ducat et al. concluded that versatile firesetters may have a more chronic course of antisocial behavior, which is much in line with our finding.
Traumatic secondary OA has an evidence base derived from animal models, but there is a paucity of animal studies examining the more chronic course of primary knee OA.
Studies show that depression that initially appears later in life is linked to a more chronic course of illness [ 39, 40].
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However, individuals with more chronic courses of major depression had significantly shorter leukocyte telomeres than healthy controls, suggesting this may be a cumulative marker of chronic depression.
Thus, our results may not be applicable to patients with more chronic courses of AN.
8 Gambiense HAT has a more chronic progressive course with an average duration of almost 3 years.
Interestingly, immunization with mouse CII induces arthritis in a smaller number of mice but gives a more chronic disease course than immunization with heterologous CII [ 8, 9].
For bipolar disorder, a randomized controlled trial of CBT for BD found that CBT was ineffective for patients with a more severe, chronic course of illness (Scott et al. 2006).
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CEO of Professional Science Editing for Scientists @ prosciediting.com