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However, our experience using ZFNs in human cells suggests that ZFN-induced homologous recombination can be much more challenging to implement than ZFN-induced mutagenic NHEJ-mediated repair.
They are more challenging to implement than SMLM techniques, but are both currently commercially available from the main microscope manufacturers.
Indeed, in our cohort study, anthropometric assessment requirements, such as observer training and data collection supervision, were revealed to be more challenging to implement than first conceptualized.
The continuous-adjoint requires less resolution and usually converges more quickly than the discrete-adjoint but is more challenging to implement.
Community network meetings were more challenging to implement.
In science, specialization seems to afford more opportunities to plan for inquiry-based experiences which may be more challenging to plan and implement for self-contained teachers with a divided focus.
It is more challenging to be implemented successfully than ERP system.
"It's challenging to implement but much less challenging than an international criminal court, which we've done," Martinez-Fraga says.
These approaches are both technically challenging and more expensive to implement than traditional mouse model approaches.
The CBT components were mainly viewed positively but regarded as more challenging to learn and implement.
Our previous experience of implementing STAR in chemotherapy clinics at MSKCC is that patients find it no more challenging to use than an ATM machine[ 15].
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