This interest stems from the need to further develop the evidence base on the effectiveness of healthcare and public health interventions, and an awareness that evaluation becomes more challenging as interventions move along the spectrum from 'simple' towards more complex interventions [ 1].
There is continuing interest among practitioners, policymakers and researchers in the evaluation of complex interventions stemming from the need to further develop the evidence base on the effectiveness of healthcare and public health interventions, and an awareness that evaluation becomes more challenging if interventions are complex.
Although it is more challenging to design interventions for people with a broad range of conditions, interventions that seemed more effective in this group were those that targeted specific areas of concern for patients.
When the primary change is in arterial resistance, as when a vasopressor is deployed, the situation is more challenging since the intervention is aimed at generating a blood pressure increase, but the effect upon SV may be in either direction.
Chronic inflammation and its sequelae such as band keratopathy, posterior synechiae, and cyclitic membranes make surgical intervention more challenging and outcome less certain.
Small simple acute tears can heal well without surgery, but chronic larger tears are more challenging and can require intervention.
Indeed, most people -- even the smartest, most level-headed government officials and military experts -- find that doing so is agonizingly difficult and much more challenging than the original intervention.
These technological advances also make fault diagnosis and maintenance interventions much more challenging, since these operations require a deep understanding of the entire system.
Making a financial intervention all the more challenging or not even possible till it's too late.
