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"This is a more challenging event in the history of the lodging industry than almost any other," said Bjorn Hanson, clinical professor of the Jonathan M. Tisch Center for Hospitality and Tourism at New York University.
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Stress can also temporarily decrease our IQ (as seen in this study of the effects of poverty), making it much more challenging to process an event accurately.
It is extremely difficult to predict the outcomes of macroeconomic events and even more challenging to predict how those events will impact financial markets.
Both simultaneous and non-simultaneous target events are considered, though clearly simultaneous events are more challenging, as the problem of resolving the association of measurements to events has greater ambiguity.
The extra layers of endosymbioses, the drastic reduction of endosymbiont, the extra waves of EGTs, and horizontal gene transfers (HGTs) all add to the complexity of these cells, and unraveling their evolutionary histories becomes even more challenging where the symbiotic events are old or at later stages of integration or endosymbiotic reduction.
In addition, the use of multiple tools for the more challenging aspects (gene/protein NER and event extraction), allows users to query and interpret data depending on whether it was extracted by one or more components of the system.
In addition, the inclusion of the large number of rare transcripts in Ensembl significantly increased program runtime and made validation events much more challenging to interpret unequivocally.
Compared to SNPs, large structural variations (SVs), such as copy-number variations (CNVs), copy-number neutral inversions, mobile-element insertions (MEIs), deletions, translocations, and combinations of these events, are more challenging to detect and characterize.
Our results show that i) model selection and parameter estimation improve with larger sample sizes and ii) consistent with previous work [ 19, 20], recent demographic events are more challenging and require substantially larger sample sizes for accurate inference.
Wrangling commitments for an actual date for hosting an event has been more challenging.
He worked every day for 50 years on a golf course and never played the game, even as the boys won local caddy tournaments, then more challenging local tournaments, then pro tour events.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com