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But sooner or later there will have to be a ruling on a more central issue: Do exiting ministers have the right to make off with their paperwork?
"For Democrats, health care is a much more central issue," said David L. Friedman, an Obama fund-raiser who created a chain of nursing homes in Maine.
Michael Jonathan Grinfeld, an associate professor at the University of Missouri's journalism school, offered this provocative view: I remember a time when "the war on poverty" was a more central issue challenging the American conscience than the recent "wars" we've fought.
As innovation becomes an ever more central issue for the development of firms and world economies, so the need for improved assessments of innovative performance grows more urgent.
Fiorina's record as CEO of Hewlett-Packard will likely be a more central issue to her campaign than her stance on social issues, said Whelan.
Stone added that he thought Mueller's primary investigative focus was an obstruction case rather than the more central issue of collusion, which presumably would be the greater risk to Manafort. .
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The more central the issue is to oneself, the greater pressure one exerts on the partner to change.
Under the Dodd-Frank act, the Treasury has become more central to financial issues, and there are a lot of Dodd-Frank reforms still to be carried out.
This year's Republican convention is likely to produce its own cloud of litigation, and once again, both the behavior of demonstrators and the reliability of police intelligence could be a central issue: more than 800 people were arrested in St .Paul and Minneapolis over the last week, and dozens of others were detained, handcuffed, photographed and searched without arrest.
The success in using the GP, short for the generalized particle dynamics method (Fan, 2009), with the cohesive zone method (CZM) to bridge crack propagation at the atomistic and mesoscopic scale (Xu et al., 2016) brings more attention to its central issue: simulation accuracy of crack-tip parameters.
Before more fully exploring the central issue of multiple testing, it should be briefly mentioned that the fold-change criteria is somewhat dubious.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com