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Male mice also had more cellular deficits in the striatum.
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Using a rat model of FXS we demonstrate that several key cellular deficits in hippocampus that result from Fmr1 deletion are conserved between species that separated in evolution more than 12 million years ago (12).
"By 2002, a lot more cellular phones are going to have Internet access than PC's".
"Ubuntu" shows up in a more cellular level as well.
In summary, rats show species-specific behavioural deficits in the absence of FMRP despite conservation of cellular deficits.
Several of these cellular deficits have been linked to greater inflammation and proinflammatory cytokine production [ 6].
These data indicate that Golgi abnormalities represent a sensitive marker for cellular deficits in motor neurons.
To further investigate potential cellular deficits underlying the CHS phenotype, we examined the functionality of cultured splenic T cells.
Such expression profiles are informative as to the underlying cellular deficits that engender neurophysiological phenotypes associated with cognitive decline.
This differential expression of stress genes in different motor neurons may be explained by heterogeneity of cellular damage responses triggered by different cellular deficits.
These in turn lead to a decrease in essential cellular functions such as protein translation or mitochondrial respiration and the induction of innate immune responses that may be specific to the cellular deficit induced.
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