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As SF could promote more cell attachment and growth than CS from Figure 8, it is apparent that SF also promotes cell spreading and lead to flat morphology of cells compared to CS which leads to a round-cell morphology.
If the polar surface energy of the cell is greater than that of water, more cell attachment would be expected on materials that are higher in both dispersive and polar surface energies.
Thus, NT10 (30 nm in diameter) with high hydrophilicity induced more cell attachment at an early time than Ti because of greater protein adhesion.
Interestingly, there appeared to be more cell attachment in our long-chambered design than our short-chambered design where holes were in the gel modeling the brain parenchyma.
The key variance in total cell attachment appeared at hole 5, where there was significantly more cell attachment on shunts in the long-chambered design than on shunts in the short-chambered design (P < 0.05, data not shown).
Thus, OCT/PLGA-TNTs with more protein adhesions induced more cell attachment at an early time than Ti, and TNTs with the fewest protein aggregates induced the least attachment.
Similar(54)
The surfaces with lower crystallinity facilitated more rapid cell attachment and increased proliferation rate, despite having a less heterogeneous surface topography.
More importantly, cell attachment and growth of human keratinocyte cell line HaCat on the nanofiber PHA matrices showed a notable improvement over those on PHA matrices prepared via an ordinary solution casting method.
Ab-RGD and Ab-HepIII promoted significantly more initial cell attachment compared to PBS control.
More importantly, cell attachment to the ECM also determines the nature and context of how cells interpret and respond to cytokine and growth factor binding [ 52].
However, 40 U/g MTGase-prepared MTGH hydrogels were more suitable for cell attachment.
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