Sentence examples for more causal variants from inspiring English sources

Therefore the potential to detect more causal variants is increased.

However, when considering simulations with two or more causal variants, CAVIARBF outperformed the other methods.

Discovery of more signals and more causal variants for type 2 diabetes and obesity is likely to allow more detailed examination of these issues.

This raises the possibility that rs328, at least in Caucasians, might not itself be a functional locus, but in LD with one or more causal variants.

There is strong experimental evidence that B7 is in fact linked to one or more causal variants: in a separate study conducted by our group, the presence of a causal variant on chromosome 7 was demonstrated using consomic mice created from the highly susceptible A/J strain and the highly resistant C57BL/6J strain.

Although the MHC2TA -168A>G polymorphism has convincingly been associated with MHC2TA gene expression, it is unclear whether the polymorphism itself is functional or whether it is in linkage disequilibrium with one or more causal genetic variants.

Within the model framework considered here, we cannot consider weaker selection and hence more common causal variants.

3 However, at this stage, it is uncertain whether these polymorphisms play a causal role or are merely tagging one or more unknown causal variants.

Resequencing of the LD block tagged by rs10865710 may be needed in order to identify one or more SSc causal variants.

Model (b) incorporates fewer and, on average, more common causal variants than does (a), and thus represents a lower degree of allelic heterogeneity.

This shows that type one error rates are similar, that power is similar for two SNP models, but that power can be increased by averaging over three SNP models compared to two SNP models, particularly when there are really three or more distinct causal variants (Fig.  4).