Sentence examples for more bulky substrates from inspiring English sources

While less sterically congested alkyl amines coupled readily (entry 10), reactions with more bulky substrates (entry 11) were slower and comparable to the background reactions.

Consequently, the addition of organic additives seems to hamper the binding of the more bulky substrate benzaldehyde to the donor binding site more than the acceptor binding site, yielding smaller 2-hydroxy ketones.

The crystal structure of BlaC reveals a bigger and more flexible active site than most β-lactamases.[ 13] This important structural insight led us to hypothesize that BlaC could tolerate more bulky lactam substrates to provide specificity and thereby serve as a unique biomarker for Mtb detection.

The ability of these MAL mutants to catalyze the amination of substrates with a small (e.g., F) or more bulky (e.g., CF3 and CH3) substituent at the ortho, meta, or para position of the aromatic ring (i.e., 2 b– j) was tested by using H NMR spectroscopy (Table  2).

The limited space of the alternative binding pocket is also the reason why models of anti-Prelog complexes were only obtained for substrates with methyl groups (1, 21, 22), but not for those with more bulky, substituted alkyl side chains such as 28, 29, or 43.

The F332S mutation broadens substrate specificity of the WaaL glycosyltransferase allowing it to efficiently accept a significantly more bulky initiating MurNAc with an attached oligopeptide stem.

This made a difference in several ways: (1) the receptor species used for the pre-incubation was more bulky and it should therefore melt larger holes into the gel, (2) it was applied in its substrate-bound conformation and (3) the pre-accumulated NTR·cargo complex could be directly visualised and quantified within the gel.

She's so much more bulky than he is.

No more bulky laptops with increasingly unnecessary components.

Mike: Nothing more bulky in that bag than an Oyster card and a stiffie invite.

With several bulky substrates high enantioselectivities with E>100 were obtained.