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Accordingly, Vasp−/− mice developed significantly more brain edema (0.8 mm3±0.4 mm3 versus 1.7 mm3±0.5 mm3, respectively; p<0.0001).
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More severe neurological deficits, brain edema and neuronal damage were also observed in high-altitude ICH.
Previous reports suggested that HS was more effective in treating brain edema resulting from cerebral hemorrhage, ischemic or traumatic brain injury, as compared with equiosmolar doses of mannitol, in animal studies [ 9, 12] and clinical trials [ 14- 17].
The expansion of hypertensive intracerebral hemorrhage occurs earlier, and brain edema emerges more gradually.
In this trial, subjects with the ApoE4 genotype were much more likely to develop vasogenic brain edema at lower doses of this antibody [ 15].
These results suggest that, when compared to results of the T group, these morphological changes corresponding to brain edema were more prominent in the AT group after 6 h.
The decreased ADC posttrauma with acute alcoholism indicates more restricted diffusion, suggestive of cytotoxic brain edema at these time points, whereas the observed increase in ADC after injury suggested the development of vasogenic edema.
Another possible explanation might be that the quantitative determination of BBB permeability defect by EB dye extravasation is more sensitive than the SG method for determining brain edema.
For each case, PTBE was evaluated in MRI by an experienced radiologist and graded by Steinhoff classification as follows: 0, no edema; I, peritumoral brain edema limited to 2 cm; II, peritumoral brain edema limited to half of the hemisphere; III, more than half of the hemisphere [ 16].
Then the 32-year-old Mr. Lee died suddenly of a brain edema.
Evaluation of brain edema caused by influenza associated encephalopathy (IAE) model using Evans blue administration.
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