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If NSA is applied to a dataset with both tumoral and control samples, the detection of CN changes could be even more accurate than using MCS (especially if NSA removes the batch effects) because of having more and (what is more important) more appropriate samples to calculate the references.
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30 Therefore, in some settings serum, rather than urine, may be more appropriate sample.
Therefore, the S. PAU participants constitute a better representation of the general Caucasian population and are the basis of our study, while the MARTHA population is a more appropriate sample for evaluating the role of the new genetic markers in subjects with overrepresented FVL and PT mutations [ 8].
Firstly, while previously release score database [29] used nearest neighbor interpolation, we used area interpolation implemented in OpenCV [55] for more appropriate down-sampling simulation.
In contrast, Pletinckx et al. indicated that the combination of oropharyngeal and cloacal swabs may have been more appropriate for sampling broilers [ 47].
Our results correspond with previous reports that GBS colonization of rectal samples is 18% to 24% higher than that of vaginal samples [ 24, 25] and with those of other studies that find rectovaginal sampling more appropriate than vaginal sampling only [ 7, 26, 27].
Moreover, the smaller size of the standard deviations makes it use more appropriate for smaller samples, as we will see in Study 5.
Studies that include patients with one- and two-vessel disease provide a more appropriate, "real world" sample population, and yield terciles that compare appropriately to our group.
This final set of items yielded item difficulty levels that were more appropriate to each sample group.
Normality of the distribution of all measurements was confirmed using the Shapiro-Wilk test, which is more appropriate for small sample sizes than the Kolmogorov-Smirnov test.
Fisher's exact test was also used for assessing the differences between substance use distributions and patterns as this is more appropriate for smaller sample sizes.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com