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This intermediate outcome was used in the analysis because patients in our study population have not been followed over a long-enough time period to allow for a more appropriate outcome to be measured.
23 The authors argued that waist circumference is not dependent on lean body mass and is therefore a more appropriate outcome when studying effects of physical activity.
Quality of life maybe a more appropriate outcome of interest than health status since it may take years to change health status through lifestyle interventions.
Future research should focus on developing more appropriate outcome measures, health economic methods, and exploring the use of quality of life or capability measures to determine effectiveness from a more holistic perspective.
In addition, more appropriate outcome measures than pCR should be defined for 'luminal' tumours, that can be assessed in a replicable manner after the completion of local treatment, and that correlate robustly with relapse-free survival.
In a population that includes subjects who will never progress to AD and others who will progress to AD (such as a healthy population), it could be argued that conversion may be a more appropriate outcome.
Similar(49)
∘ Moderate (Rankin 3): balance training/standing, global strengthening, therapeutic gait, adaptation to orthoses and walking aids, spasticity control, functional speech/adaptation to alternative communication resources, improving swallowing skills, independence in activities of daily living, cognitive-behavioral interventions to shape more appropriate outcomes and post discharge plans.
∘ Moderate (GCS 9 12): balance training/standing, global strengthening, therapeutic gait, adaptation to orthoses and walking aids, spasticity control, functional speech/adaptation to alternative communication resources, improving swallowing skills, independence in activities of daily living, cognitive-behavioral interventions to shape more appropriate outcomes and post discharge plans.
It can be argued that for our study goals, the RMDQ-score would have been a more appropriate primary outcome measure than the NRS back pain score.
Whilst this interactive learning tool did not improve knowledge over and above self-directed learning, an improved tool might be more effective and efficiency might be a more appropriate primary outcome for further research.
However, for continuous outcomes, the mean difference (MD) is recommended when outcomes use different scales in each group, while standard mean difference (SMD) is more appropriate when outcomes have the same scale in each group.
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