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Expression may have been upregulated had cells been injected in a more appropriate microenvironment, e.g., via orthotopic implantation [ 40, 41].
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The results for chondrogenic and osteogenic differentiation of progenitor cells on each scaffold indicate that the lower modulus PCL fibers provided more appropriate microenvironments for chondrogenesis, evident by a marked up-regulation of chondrocytic Sox9, collagen type 2, and aggrecan gene expression and chondrocyte-specific extracellular matrix glycosaminoglycan production.
Consequently, the presence of the synthetic PAA component in the formulation of the scaffold did not influence either hADSCs behavior in contact with the material or the evolution of the adipogenic differentiation process, but it ensured a more appropriate 3D microenvironment for cells, resembling in vivo conditions.
Identification of mechanisms influencing muscle regeneration by modulation of its microenvironment may, therefore, be more appropriate.
"Tormentor" feels more appropriate.
Biting is far more appropriate.
Fortunate would be more appropriate.
"Shopping spree" is more appropriate.
"Der Bomber" became a more appropriate moniker.
A more appropriate measure might be underemployment.
A more appropriate word is "complicit".
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CEO of Professional Science Editing for Scientists @ prosciediting.com