The multiple sequence alignment was produced using the T-Coffee method [68] more appropriate for alignment of proteins with low percentage of identity as BBS6 and CCTα.
However, in reality RIP depends upon the alignment of two similar regions of double-stranded DNA [ 23] and therefore it is more appropriate to use alignments of repeat families to identify and quantify RIP.
These parts of the sequences apparently were allowed to adapt to the new function more freely, suggesting that, after all, the class-5 alignments might, in spite of their lower DIALIGN score, be more appropriate than the class-3 alignments.
This result is founded on the more appropriate band gap and better band alignment with the hybrid perovskite, leading to the faster charge carrier mobility, improved charge transfer and reduced exciton recombination.
Finally, we show that we can produce more accurate alignment boundaries, even without true domain boundary knowledge, by using the initial BLOSUM62 alignment identity to specify a more appropriate scoring matrix.
One possibility is that the strong bedding system maintains the head in a more appropriate posture and/or moves the spine into a better alignment, particularly when subjects suffer from sleep-related respiratory disturbances due to mechanical causes [ 1].
The presence of fissure eruptions (as noted in Harrat Rahat) may also justify an increase in buffer zone distance, and, if multiple fissures show similar alignments, anisotropic buffer zones may be more appropriate.
It has been shown that an alignment of only primate sequences provides a potentially more appropriate model for human genetic variants [ 40].
This way, the method can produce global as well as local alignments of the input sequences, whatever seems more appropriate.
We agree that the improvement in contig lengths mainly stems from the multiple alignment with consensus representation of the components, which seems to be a more appropriate output for contigs belonging to different subspecies due to variations.
