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In turn, these dynamic TPS scaffolds provide more alternative pathways during the cationic rearrangements leading to additional sesquiterpene products.
Therefore, facultative organisms have likely more alternative pathways than non-facultative organisms, which is reflected by their bow-tie structure.
These aspects strongly suggest that one or more alternative pathways leading to the expression of certain genes associated with the delayed activation of NF-κB and AP-1 probably exist in TLR4 signaling.
Moreover, our results support the hypothesis that DSBs are repaired by one or more alternative pathways and they are not independent of each other as evidenced by the reciprocal relationship between markers of HR and NHEJ of DNA DSB.
This effect of the hormone does not involve the pregnane X receptor/steroid and xenobiotic receptor (PXR/SXR) [ 42] that is usually implicated in MDR1 gene expression, thus indicating the existence of one or more alternative pathways for regulation of MDR1 expression.
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Interestingly, these findings do not modify our current view of the general organization of C1 pathways, but show that many more alternative enzymes or pathways than initially assumed carry out each of the basic steps of methylotrophy.
However, with this research showing that for many graduates, the costs of university education outweigh its personal economic benefits, we need a much stronger focus on creating more high-quality alternative pathways into the workplace, such as higher level apprenticeships, so we really do achieve parity of esteem between the two routes".
We need a much stronger focus on creating more high-quality alternative pathways into the workplace, such as higher level apprenticeships, so we really do achieve parity of esteem between the two routes".
Such a mutant would also allow us to test whether the remaining acetate production in our AK mutant is due to complementation of the enzyme activity by butyrate kinase or if one or more alternative acetate-forming pathways operate in C. acetobutylicum.
More drugs potentially targeting alternative pathways need to be evaluated in combination with sorafenib.
We discuss two different strategies to initiate a process of identifying a focused sustainability challenge, and co-defining and co-designing alternative pathways to more sustainable food systems.
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more parallel pathways
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