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The firm's name has had more alterations than Oprah's clothes!
We confirmed that stage T1 tumors had significantly more alterations than stage Ta tumors (p = 0.008, Mann-Whitney-test).
Overall, CMA detected 32% more alterations than QF-PCR and karyotype, including eight conditions with rather poor prognosis for postnatal development (Table 3).
This fact has already been suggested in a previous work using microsatellite markers and showing that tumors in non-smokers had more alterations than that of smokers [ 23].
The most dramatic difference in genetic alteration frequencies are observed between the pair of reciprocal F1 hybrids, with calli and regenerants of N/9 (Nipponbare as maternal parent) showing more than 30-fold more alterations than those of 9/N (93–11 as maternal parent), and nearly all the alterations are of the loss-type.
Additionally, conversions other than C-to-U in cotton, as well as other crops, suggest that chloroplast genomes may be accumulating considerable amounts of nucleotide substitutions, where some genes might accrue more alterations than others, such as the petL and ndh genes that have a high frequency of RNA editing [ 55].
Similar(54)
To prevent any more altercations, more than a dozen policemen stood along the 50-yard line as the teams went through warm-ups.
Conversely, the frequency of CRCs in the group showing three or more alterations was higher in M+ than in M− tumours (34/130=26% vs 9/72=12%; P=0.023).
They typically contain more chromosomal alterations than primary tumours, and the aberrations are more confined.
Overall, growing tumours had significantly more molecular alterations than the nongrowing ones.
Solid tumors usually carry more genomic alterations than hematological malignancies [ 58– 60].
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Justyna Jupowicz-Kozak
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