Discussion Even though the benefit of LTVV applied for all ICU patients is still to be demonstrated, our results show that women are exposed to much more "aggressive" mechanical ventilation with potentially harmful consequences.
Compared with control patients, markedly higher hospital mortality, ICU LOS, hospital LOS and hospital costs, and more aggressive interventions (mechanical ventilation, central venous catheterization, and urinary catheterization) were observed in matched patients with severe sepsis and IFI.
Their results indicate that MV without PEEP and during one lung ventilation is more aggressive to the lungs and can promote a more intense ventilation-induced injury even after a short time.
With the potential advent of near-patient testing for BNP, this may prove to be a valuable adjunctive assessment to promote both a more successful and possibly a more aggressive approach to liberating patients from mechanical ventilation.
The question remains of whether female patients were more aggressively resuscitated, leading to fluid overload and need for mechanical ventilation, or if they received more aggressive anti-microbial therapy.
NAVA provides a less aggressive ventilation requiring lower inspiratory pressures with good results for oxygenation and more comfort for the children.
These findings would correlate with a higher OI in ulinastatin-treated cases and a more rapid extubation time consequent upon a more aggressive policy by intensive care physicians to more rapidly wean their patients from mechanical ventilation.
Patients with mild ARDS typically only require non-invasive treatments, whereas patients with moderate to severe ARDS are more likely to require more aggressive interventions, including prone positioning, recruitment manoeuvres, neuromuscular blockage agents, inhaled nitric oxide, high frequency oscillatory ventilation and even extracorporeal membrane oxygenation.
Boot is rather more aggressive".
