Sentence examples for more aggressive variant from inspiring English sources

Among the main objectives for generating the ApcMin/+/Faslpr mice was to determine if a more aggressive variant of the ApcMin/+ mouse model would evolve.

LCC6 is the more aggressive variant of MD-MB435.

About one tenth develop a more aggressive variant leading to a more severe deformity of the spine and thorax [ 2].

For instance, SIP1 was found to be hypermethylated in poorly metastatic breast adenocarcinoma cells, but hypomethylated in a more aggressive variant of this cell line [ 28].

Its clinical presentation is similar to the classic form but with a more aggressive variant that responds poorly to conventional treatment.

Such results could be a consequence of including two cases of subtotally resected tumors and, more importantly, the more aggressive variant of astrocytoma with pilomyxoid features [ 6].

Conversely, the expression signatures of primary tumors generated by more aggressive variants, and their matched metastases in the lungs and lymph nodes, all tended to converge.

The appearance of nullipotent EC cells may reflect selection of more aggressive variants during cancer progression.

Nevertheless, a subset of patients develops local recurrence or distant metastasis and may die from DTC, indicating the possibility of more aggressive variants of this carcinoma.

It is reasonable to assume that AD progresses more rapidly when the disease is detected at younger ages, as hereditary and more aggressive variants of the disease may have a greater influence on the outcome [ 37].

These DTCs might transform into more aggressive variants and grow out to overt metastasis [ 7] and/or they may recirculate to other secondary organs or even back to their primary tumor site [ 12, 13].