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Several weeks later, the analysts made a more aggressive presentation to White House officials.
Familial adenomatous polyposis and Lynch syndrome are the most frequent hereditary CRC syndromes with a more aggressive presentation, earlier onset and strong familial aggregation.
ENB in younger patients seems to have a more aggressive presentation than in adults with a larger proportion of cases with advanced disease.
Reasons for poorer survival among AA women are unknown [ 5], but are likely multi-factorial, including differences in treatment, access to care and comorbidities, as well as more aggressive presentation [ 6– 9].
Despite their more aggressive presentation, IgAN/ANCA+ patients responded better to immunosuppression than IgAN/ANCA– patients, with a higher dialysis withdrawal post-immunosuppression (75 versus 0%, P = 0.01) and with a non-significant trend for less ESRD at 6 months (0.77 versus 0.26 events/person/year, P = 0.09).
The current study attempts to pinpoint specific genetic and epigenetic features of CRC cells, which are both associated with the observed more aggressive presentation of CRCs expressing HIF2 α and CA9 in their surrounding stroma, and impact on one of the hallmarks of cancer, namely regulation of apoptosis under hypoxic conditions.
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These circumstances imply that large parathyroid adenoma (LPTA) patients could have more aggressive clinical presentations.
This may be due to more aggressive tumours at presentation or the higher average age achieved by female patients.
They observed more aggressive disease and earlier presentation in families with single generation involvement, as in our present case family.
To break the ice during the first visit, a face-to-face approach was preferred to a more "aggressive" projection of a presentation.
In case of severe nodular/bronchiectatic disease or fibrocavitary presentation, a more aggressive regimen is recommended.
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more aggressive defense
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more positive presentation
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