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Extraosseous myeloma is more aggressive, occurs in a younger age group (average age 50 years) and is associated with worse survival than conventional myeloma.
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Progression from benign hyperplastic melanocytes to more aggressive disease occurs when tumor cells begin to break down and invade through the basement membrane, and subsequently migrate into the collagen-rich dermis [2].
CONCLUSIONS: Black-white racial disparities in stage at diagnosis appear to be related to higher-grade lesions and more aggressive histologic subtypes occurring more frequently in black patients with endometrial cancer.
Progression to a more aggressive tumour phenotype occurred in 17/78 patients (21.8%) in this series.
EBV may play a limited role in the initiation of lymphoma in the immunocompetent patient, but the virus may be of importance in progression of the disease in those patients with more aggressive tumors, as immunosuppression occurs.
In Figure 9, the drop in HP traffic throughput with an increase in the total number of traffic flows in the network is attributed to the more aggressive channel contention that occurs between the increasing number of HP flows in the system, thereby leading to higher collisions and hence lesser overall HP throughput. .
However, patients may develop resistant disease; in addition, transformation to a more aggressive subtype of lymphoma occurs at a rate of 2 3% per year.
These results suggest that the upregulation of xCT occurs in more aggressive GBM tumors.
These data indicate that EMT preferentially occurs in more aggressive breast tumours of the basal phenotype.
Estrogen receptor (ER -negative tumors, which arER -negativessive tumorsR-positive tumors, occur more frequently in African American which tharein Caucasian womoreaggressiventhanute to apparent disparities in outcomes.
When insulin is administered, hypoglycemia is a foreseeable consequence, and more likely to occur with more aggressive and narrow BG target ranges.
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