There were some more aggressive lines of questioning, too.
Indeed, evaluation of heparanase expression in breast cancer cells reveals that more aggressive lines, such as MDA-MB-231 and MDA-MB-435, present high levels of heparanase, whereas MCF-7, a nonmetastatic and poorly invasive luminal breast cancer cell, presents low levels of the enzyme [ 7].
You have to take a more aggressive line against him, for sure.
I thought Comme des Garcons was pretty interesting, and surprising a more aggressive line of attack than we've seen from Rei Kawakubo in awhile.
They have taken a more aggressive line on Hong Kong as President Xi Jinping attempts to consolidate his power at home and China's influence in the region (see next two stories).
Instead, they watched in disbelief as Rahlves, a 27-year-old Californian, took the gold medal in the super-G after a brilliantly plotted run in which he sometimes took a more aggressive line than the famously aggressive Austrians and managed to keep his nerve and balance.
On at least three crucial issues -- Afghanistan, Libya, and the bin Laden raid -- Clinton took a more aggressive line than Gates, a Bush-appointed Republican.
Quoting Time writer Michael Crowley, Henwood writes that, "On at least three crucial issues -- Afghanistan, Libya, and the bin Laden raid -- Clinton took a more aggressive line than [Defense Secretary Robert ] Gates a Bush-appointed Republican".
Nevertheless, mTSPO targeting with PK11195 - which impinges on Ca2+ homeostasis [ 3] - raises C2-ceramide cell death in MCF-7 and in the more aggressive line of adenocarcinoma MDA10 - characterized by an increased mTSPO/VDAC ratio of expression.
Immunoblot analysis of equal protein amounts of cell lysates with anti-VEGF antibody revealed that the less-aggressive cell lines (T47D and MCF7) expressed less VEGF than the more aggressive cell lines SKBR3, MDA-MB-231 and MDA-MB-453 cells.
Indeed, less hornerin fragmentation is observed in the more aggressive MCF10A lines, similar to less fragmentation observed in the ER/PR negative breast cancer cell lines, which are inherently more invasive and tumorigenic compared to the ER/PR positive cell lines [ 35, 46].
