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Ossifying fibromas typically do not cause root absorption, which is a feature of more aggressive lesions such as ameloblastomas, and unlike radicular or dentigerous cysts, there is no association with unerupted teeth [4].
Therefore, it is important to identify more aggressive lesions at an earlier stage for rigorous treatment.
Furthermore, no mutations were detected in depressed tumors, indicating existence of different molecular pathways for these clinically more aggressive lesions.
Interval cancers present with increasing frequency through the screening cycle and are faster growing, pathologically more aggressive lesions.
However, the metastatic nodules are generally circular with regular contour, especially in more aggressive lesions, such as those of sarcomatous origin [ 28].
More aggressive lesions extending lateral to the maxilla, or lesions where carcinoma is detected, may require a combined approach with external incisions, or even staged with a subsequent open approach.
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Histology is an unreliable means of predicting clinical behavior, but this study has identified some morphologic and phenotypic features that may indicate a more aggressive lesion.
Histological dedifferentiation may occur within a portion of the well-differentiated liposarcoma, resulting in a more aggressive lesion, which is more prone to metastasise and carries a worse prognosis [1].
On the other hand, abnormalities in podocytes might progress to a more aggressive lesion that would be responsible for an increased feedback loop between circulating molecules, thus leading to recurrent or even more severe forms of renal failure [ 55].
Thus, ST-3 seems to have similar effects on breast cancer cells derived from more differentiated tumours and on cells from more aggressive and dedifferentiated lesions.
Internationally no association has been found between the thickest tumours and patient or physician delay, [ 35- 38] rather, it is probable that the greater thickness can be accounted for by more aggressive, rapidly growing lesions [ 30].
More suggestions(15)
more aggressive tumours
more new lesions
more aggressive cases
more tubulointerstitial lesions
more aggressive reductions
more dispersed lesions
more extensive lesions
more aggressive tumors
more aggressive treatments
more aggressive species
more numerous lesions
more chronic lesions
more measurable lesions
more serious lesions
more specific lesions
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