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The non-SP cells induced by macrophage-like cells showed more aggressive characters, which increased cell migration compared with the control cells and showed some fraction of SP phenotype.
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In spite of the importance of ER as a therapeutic target, ER-negative tumors have a more aggressive character and a different metastatic pathway than ER-positive tumors.
Thus, the striking expression of mcl-1 mRNA observed in established tumor cell lines may be a reflection of their more aggressive character.
Studies have shown that basal-like and HER2-overexpressing tumours have a more aggressive character, resulting in an unfavourable patient outcome compared to the Luminal tumour types.
It has previously been suggested that this may be caused by the more aggressive character of disease in this group of patients, requiring more invasive surgical procedures and chemotherapy (Kroman et al, 2000; Colleoni et al, 2002).
The sharp nose, long hood and steeply raked windshield emphasize the new SLK's more aggressive, dynamic character".
Slim was a far more aggressive and raw character than Eminem and the album was picked up by Dr Dre and released in 1999 to huge commercial success.
Haley has a black belt in Kenpō, but described Rorschach's attack patterns as sloppier and more aggressive due to the character's boxing background.
I feel like my character's more aggressive.
Fidler initially played the straight man, but as the group became more aggressive he developed into a character who was naturally happy and caring but frequently victimised by his fellow band members.
Those characters seem much more aggressive than you. A. Good.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com