Sentence examples for more aggressive cell from inspiring English sources

HIF-2α is low or absent from the more aggressive cell lines.

The result is relevant for application in multibit technology, and opens the way to more aggressive cell scaling rules.

Also, in cases of neuroendocrine carcinoma, the efficacy of chemotherapeutic combination regimens such as etoposide plus cisplatin and irinotecan plus cisplatin has been reported [19, 20]. Lee et al. proposed that treatment should focus on the more aggressive cells of the tumor because the clinical outcome of this mixed tumor follows that of a more aggressive cell type [4].

We further investigated the role of ACSL4 using small hairpin RNA (shRNA) to disrupt the expression of endogenous ACSL4 in the more aggressive cell line MD-MB-231.

In addition, more aggressive cell lines exhibited larger complex clusters.

E-cadherin expression decreased, and c-met expression increased progressively in more aggressive cell lines.

Studies by other researchers have shown that such genetic variety in tumors can produce faster cancer cell evolution and lead to more aggressive cells.

Pathologists can distinguish between cancers that look particularly aggressive and those that do not, but there is a real possibility that even if tissue obtained at a biopsy has only less aggressive tumor cells, more aggressive cells might still be lurking in the prostate.

Alltogether our findings have important implication for understanding the origin of cancer and the possible use of asymmetric self-renewal biomarkers to target more aggressive cells.

In this work, we state that COX-2 expression in the more aggressive cells is controlled by ACSL4 through the generation of lipooxygenase metabolites since inhibition of lipooxygenase activity blunted ACSL4-dependent increase in COX-2 expression.

First, it can be postulated that the post-transcriptional rRNA processing is more efficient in the more aggressive cells (three pathways) compared to the control cells (two pathways) and that this activation of post-transcriptional processing is required, in addition to transcriptional activation, to provide the required amount of cytoplasmic ribosomes.