Sentence examples for more aggressive antimicrobial from inspiring English sources
Women with diabetes require longer and more aggressive antimicrobial treatment for UTI, and have more recurrences of their UTI than non-diabetic women.
It is possible that more aggressive antimicrobial therapy associated with chronic P. aeruginosa infection could play a role; however, the precise mechanism is as yet unknown and warrants further study.
Although mixed Candida/bacterial BSIs are not predictive for a poor prognosis with appropriate antimicrobial therapy, more aggressive policies to clear Candida species from blood might be required in the early period of antimicrobial therapy to minimize the possibility of metastatic complications.
In general it appears that specialist #1 has a more aggressive approach to the use of antimicrobials, while specialist #2 was more conservative.
These findings suggest that bacterial DNA-positive, symptomatic patients have more aggressive sarcoidosis that persists long term and might benefit from antimicrobial treatment directed against this presumed chronic granulomatous infection.
Although appropriate antimicrobial drugs were used, our data suggest that more aggressive treatment with open drainage of the pleural effusion might have contributed to a better outcome than closed tube thoracostomy or simple thoracocentesis alone.
The more severely ill patients (those with APACHE II>18), did receive appropriate antimicrobial therapy significantly sooner (0.8 days versus 1.6 days), perhaps reflecting more aggressive clinical care or broader antibiotic coverage.
More recently, a quasi-experimental, before-after observational cohort study concluded that, after adjusting for confounders, aggressive antimicrobial therapy was an independent predictor of mortality.
Furthermore, investigators may have employed more aggressive dosing in patients with infections that were perceived to be more severe due to prior antimicrobial treatment failure or multilobar involvement, both of which were more common in the higher vancomycin trough groups.
The discovery that a staggering 80% of all antimicrobials are destined for food-producing animals, and not humans, has prompted several calls for more aggressive surveillance of agricultural and veterinary practices [ 33, 34].
