Sentence examples for more affected members from inspiring English sources

The team drew on a database of 2500 families that seemed to have an elevated prostate cancer risk because they had two or more affected members.

In subgroup analyses, three loci, at 8q24 (regions 1 and 2) plus 17q12, were significantly over-transmitted in hereditary PCa families with five or more affected members, while loci at 3p12, 8q24 (region 2), 11q13, 17q12 (region 1), 17q24 and Xp11 were significantly over-transmitted in HPC families with an average age of diagnosis at 65 years or less.

Less than half the families with three or more affected members in the Breast Cancer Linkage Consortium have segregating deleterious mutations in BRCA1 or BRCA2 [ 6].

All families included two or more affected members (the youngest affected male from each family was included in the analysis) and were collected as previously described [ 26].

* including 112 families already reported in our previous studies According to number of breast/ovarian cancer in the families, we had 75 families with 3 or more affected members and 47 families with two affected members among the "high risk" cases; 67 families had 3 or more affected members and 70 families had two affected members among the "no high risk" cases.

Analyses were done using two different sample sets, the first including all individuals genotyped and the second including only familial cases, defined as cases from families with two or more affected members.

Prevalence rate in "high risk" families was higher than that of families with 3 or more affected member regardless of age at onset (11.7%).

Significant differences between the TS + LD group and the TS - LD group were found for gender (.001), age onset (.030), age first seen (.001), age at diagnosis (.001), prenatal problems (.001), sibling or other family member with tics (.024), two or more affected family members (.009), and severe tics (.046).046

And, perhaps fittingly if unintentionally, no one may be more affected than members of Congress themselves.

Extended newborn screening can detect symptomatic maternal disorders or even more affected family members with treatable metabolic disorders.

In all, 29 patients with three or more affected family members were categorised into hereditary prostate cancer according to Carter's criteria (Carter et al, 1993).