"more advanced symptoms" is correct and usable in written English.
You can use it to describe symptoms that have worsened over time, or that are not common or typical of a disease or condition. For example, "As the disease progressed, the patient began to experience more advanced symptoms, such as paralysis and loss of sensation."
Postural sway was normal in those subjects in all conditions, but was abnormal in subjects with more advanced symptoms (UPDRS III > 20, P < 0.01).
RESULTS: Patients on higher doses of furosemide were less frequently on renin-angiotensin system inhibitors (P =.01) and had worse renal function and more advanced symptoms.
On the contrary, with my patients with more advanced symptoms, I often let them know the specific concerns I have about their condition.
As such, alternate interventions may be necessary for individuals who present with more advanced symptoms.
Patients who underwent valve replacement were older, had more advanced symptoms, and had more complex disease.
When people do start presenting, new VCTs tend to attract the people with more advanced symptoms of AIDS [ 49, 50].
Hearing loss is a more advanced symptom of ear infections, so if you begin to notice your hearing going in an ear along with other symptoms, that is definitely a reason to see a doctor.
Generally RCC tend not to cause symptoms in early stages, whereas in patients with more advanced disease symptoms are nonspecific.
RESULTS: Compared with patients who did not receive the recommended follow-up (n = 43,060), those who did (n = 30,256) were more likely to be older, white, to have received a cardiac resynchronization therapy-defibrillator device, to have more advanced heart failure symptoms, and to have nonischemic dilated cardiomyopathy.
On the other hand, tools that provide evidence of the underlying pathology might improve physician's confidence, and lead to an earlier diagnosis, by reducing the need for longitudinal follow-up and progression to a more advanced stage of symptoms.
This finding is similar to that reported by Pease et al., who found that patients over 65 years of age had a higher HAQ score at baseline [ 11], and with results derived from the Norfolk Arthritis Register showing that more advanced age at symptom onset was associated with a "steep trajectory" progression of disability [ 44].
