28 This analysis demonstrated that the association between radiographic progression and physical function was similarly important in relatively early RA (disease duration ⩽3 years) as compared with more advanced RA (disease duration >3 years), which emphasises the importance of minimising radiographic progression at all stages of the disease.
No significant trend was observed at either time point in the subset with more advanced PD (disease duration >2 years; n = 23 and 74 for baseline and final, respectively).
The fine sensing is more advanced and takes longer duration.
The discontinuation rate and incidence of adverse events seem to be more prominent in older patients, naïve to entacapone with more advanced disease, longer disease duration and higher daily levodopa dose.
21 Our data confirmed that the objective duration of the surgery was longer in cases with worse preoperative visual acuity, as more advanced cataracts require a longer duration of ultrasonic power release.
These behavioral indicators, which we use as features, range from simple ones such as number of calls, number of texts, and average call duration to more advanced ones such as the text response rate, radius of gyration, and entropy of visited places.
More advanced devices can track sleep duration and quality, heart rate and running speed, and they can be synced up with smartphone apps.
By design, the secondary cohort had longer diabetes duration and more advanced retinopathy [ 12].
This analysis was expected to isolate a relatively homogeneous subcohort with the highest exposure and likely highest rates of other cancer risks such as extreme obesity, more advanced diabetes, and, possibly, longer duration of diabetes.
An exclusively Asian population with a suggested more advanced disease due to longer duration of T2DM compared with patients in the remaining studies was listed as a possible explanation for the higher observed incidence.
