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Our proposed framework would also benefit from the inclusion of more advanced assessment of fire-human dynamics, the use of additional fire metrics (e.g., area burned, intensity, seasonality), updates in global fire products (e.g., MODIS), and the quantification of AOGCM-related uncertainty [76], as this information becomes available.
For instance, lower levels of self-reported familiarity for instrument validation items suggests this topic may represent a more advanced assessment knowledge level.
Therefore, we need to concentrate on patients and breast lesions where the appropriate action is as yet unclear and a more advanced assessment is needed.
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However, it must be further investigated to see if special analytical tools are needed to support more advanced assessments.
This case study application is conducted in a systematic fashion to clearly illustrate the various details required to implement more advanced seismic assessment studies.
Ultrasound and MRI form the basis of more advanced imaging assessment in paediatric arthritis, while cone-beam computed tomography play a role in imaging of the TMJs and conventional CT in imaging of the sacro-iliac and facet joint of the cervical spine [7].
In more advanced tumours, assessment of PODXL expression may be of value for selection of patients who would benefit from adjuvant or neoadjuvant chemotherapy.
For this case study, we considered simple correlations rather than more advanced statistical assessments in determining gene/covariate associations [ 56, 66, 67].
An important problem encountered in the assessment of pain in patients with dementia, especially in more advanced stages, is that assessment often is based on observation and interpretation of behavior, for which the validity is unequivocally established [ 5, 19, 20].
The identification that exposure assessment has been the Achilles heel for studies in environmental cancer has led to the use of more advanced techniques for exposure assessment and to considerable improvements in the evaluation of exposure.
The need for more advanced forms of risk assessment and safety oriented design approaches should however be matched to another concern expressed in the SYBHEL discussions, which relates to the impact on innovation of the current system of GMO regulation.
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