Finally, it is important to note, that while we used this method to measure simple movement trajectories in the current study, applying this method to more complex trajectories introduces additional constraints that must be considered.
In eukaryotic genomes, GC-biased gene conversion is thus expected to bring about additional constraints acting more specifically on protein segments encoded by exon terminal sequences.
These additional constraints capture more of the biological reality of metabolism than either shared metabolites or graph diffusion.
We explored the prospects for improving on the strategy of [ 1, 2] using a novel problem formulation and a series of additional constraints to more precisely bound the solution space and accelerate implicit enumeration of possible optimal phylogenies.
In this article, we explore the prospects for improving on the implicit enumeration strategy of [ 1, 2] using a novel problem formulation and a series of additional constraints to more precisely bound the solution space and accelerate implicit enumeration of possible optimal phylogenies.
Highly unequal countries see additional constraints to growth compared with more equal ones.
More generally, many flux distributions compatible with the additional constraints, including the condition on carbon precursors for lactose can be shown for both (CN) and (Ctrl) treatments.
For mammals it has been suggested that the more targets a microRNA has the more likely it is to be conserved[ 28] because of the additional constraints of having to match multiple targets.
These additional constraints will only make the random null hypothesis more stringent to refute.
Additional constraints come from environmental regulations, which are constantly becoming more difficult to assess, and require improvements in the boiler design process.
