Exact(4)
Altogether Dr. Dulac found 347 genes where either the mother's or the father's copy was more actively expressed in certain regions of the brain.
009H02 [GenBank: AAG43549], responsive to abscisic acid, and 063C04 [EMBL: CAJ13709], responsive to auxin were both more actively expressed in trichomes.
We anticipated that genes related to axonal regeneration or cell growth would be more actively expressed in the regenerator compared with the degenerator group.
Indeed, transcriptional data indicate a more sustained UPR activation in transformed cells as compared with normal cells, as several UPR-related genes and relative targets are more actively expressed in these cells.
Similar(56)
In hospital settings, patients with higher education were found to communicate more actively, expressing their concerns and preferences regarding health status and rehabilitation and received more information than patients with low education [ 22].
The posttranscriptionally silenced locus 1 with a coding region methylation acquired transcriptional gene silencing and promoter methylation more readily than a non-methylated actively expressed locus 2. Thus, the PTGS loci might be inherently more sensitive to undergo transcriptional silencing elicited either in cis 39 or by in trans (this study) factors.
To the contrary, the majority of MeCP2-bound promoters are actively expressed (9) and more transcripts are upregulated by increasing Mecp2 genetic dosage than downregulated (10).
What is much more surprising is that the H3K36me and H3K9me3 modifications, which are typically strongly associated with actively expressed and silenced genes respectively, were not correlated with Hairy-induced changes in gene expression in this study.
Genes directly targeted by MYC have been identified in various tumors [ 8, 9], but more recent studies suggest that this oncogene might be a "universal amplifier" with effects on most of the cell's actively expressed genes.
More recently, it has been observed that there are dozens of sub-nuclear foci called 'transcription factories' that are enriched for actively expressed genes [ 8].
For example, certain histone modifications distinguish actively expressed regions of the genome from regions that are not highly expressed.
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