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Additional work is needed to confirm that haplotype B PERK is the more active protein and to determine if mis-folded protein sensing or activation via auto phosphorylation is affected.
We find that, in SNAP display, the reconstituted cell free expression system PURExpress led to 1.5-fold more active protein and achieved 3.5-fold greater DNA recovery in model selections compared to the RTS 100 Escherichia coli lysate based expression system.
Overall the data support more active protein turnover in Gh fiber.
However, optimally repairing cells did have more active protein that was dedicated to growth (recall that repair machinery cannot contribute to growth).
Pycnio- and teliospores seemed to have yielded a larger number of ribosomal protein genes possibly related to more active protein production.
It was assumed that, except for the cost of the additional protein, a genotype that produces a large amount of relatively inactive protein is equivalent to one that produces a smaller amount of correspondingly more active protein.
Similar(53)
Indeed, the relatively slow rates of cell growth enabled by these first-generation de novo sequences suggest that selections for faster growth might facilitate the evolution of more active proteins.
The MnSOD Ala-containing protein showed normal transport and generated 30 40% more active MnSOD protein than did the Val form of the enzyme.
Instead of being silenced, the genes became more active and protein production increased.
The above observations are generally consistent with the prediction that the more tetramer that forms, the more active the protein is.
The increased transactivation ability of FOXC1 despite the significant reduction in FOXC1 protein levels after exposure of HTM cells to a 'high dose' of H2O2 could be due to a less stable, but more active FOXC1 protein.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com