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However, when the PERK arm of the UPR is activated by thapsigargin, PERK from haplotype B homozygote cells is more active in phosphorylating eIF2α when compared to PERK from cells homozygous for haplotype A. The haplotype that confers high risk for PSP produces the more active form of PERK, suggesting that activation of the UPR is pathogenic in PSP and not a protective response.
Although the monoclinic sulfated zirconia has been demonstrated to show some activity for alkane isomerisation, the tetragonal phase is reported to be a more active form, especially at lower temperatures (Stichert et al. 2001).
To test whether mutation to negatively charged residues might mimic autophosphorylation at this position and perhaps create a more active form of eEF2K, we created eEF2K[T348D] and eEF2K[T348E] mutants and studied their activities.
It necessitates a more active form of participation than just looking".
There have already been suggestions that perhaps powered flight evolved multiple times in the dinosaurs and early birds, with perhaps several different groups making the final jump from gliding to a more active form of movement in the air.
Finasteride, which keeps testosterone from converting into a more active form, has been used since 1992 to treat benign prostatic hyperplasia, or enlarged prostate, a condition unrelated to prostate cancer.
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The local synthesis of oestrogens depends on the activity of different enzyme families (aromatase, sulfatases, etc) to transform androgens into oestrogens, as well as compounds of weak oestrogenic activity into more active forms.
A spokesperson for Glasgow City Council said the new restriction would improve road safety and encourage more active forms of transport.
But, he says, "they should not replace other avenues of learning, replace or diminish more active forms of play, or become a babysitting device".
However, these learning resources can be accompanied by more active forms of learning, as in the case of note taking and drawing diagrams (Chi and Wylie 2014).
The app might also include more active forms of personalization, i.e., giving users a chance to say, "This is the type of thing I'd like to see".
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com