Once the definition of "behavior" expands to include such things as a shift in the trajectory of a root, a reallocation of resources, or the emission of a powerful chemical, plants begin to look like much more active agents, responding to environmental cues in ways more subtle or adaptive than the word "instinct" would suggest.
The need for more active agents is evident in light of the poor outcomes for patients with these tumors.
My research highlights the ways in which the design of websites may enable users to become more active agents in political campaigns and in the election process.
After he left, Hoover refused to allow any more active agents to be members of any military reserve.
Studies in social dialect variation and gender have repeatedly observed that women make use of a wider range of variation than men [11], [12], [53], [54] and females are often the more active agents of the diffusion of sound change compared to men (see [12], [55]; cf. [56]).
It may be that alternative models of dose intensification, using combinations of more active agents, over short time intervals, may be more effective and we have shown one such strategy to be possible.
The induction of CYP1A1 in cancer cells by dietary compounds and their subsequent metabolism to more active agents is an alternative model that can explain the cancer preventative properties of these compounds in pharmacologically relevant concentrations [ 134].
The natural product resveratrol, which has a structure similar to eupatorin, and the synthetic compounds Phortress and AQ4N are all prodrugs, which are metabolised by CYP1A1 and CYP1B1 to antiproliferative and more active agents [ 14- 16].
In locally advanced extremity STS patients, response to neoadjuvant chemo and radiotherapy (21% in our study) might associate with improved survival and quality of surgical resection, but more active agents or regimens are needed for patients who do not have a radiographic response to induction therapies (79% of patients in our study).
