This issue could be overcome with the use of secondary collimators (positioned between the sample and detector) to more accurately select the scattering angles of photons which reach the detector.
FISH has been shown to more accurately select patients than IHC, but is more costly and not routinely available.
Reiterative subdivision, profiling and high resolution validation will ultimately facilitate even deeper analysis of kidney development via the generation of tools with which to more accurately select the starting population of cells.
However, there is still a need to identify and confirm additional biomarkers that can be used to more accurately select wild type mCRC patients that will respond to anti-EGFR therapy.
A number of methods to combine diverse types of omics data across different measurement platforms and laboratories have been proposed [ 48, 49, 56], in order to more accurately select clinically relevant features or to develop better molecular signatures.
Ultimately, the assay developed herein may be used to more accurately select individual patients for potentially life-saving adjuvant therapy, while sparing those who are predicted to have a favourable prognosis.
Whilst this provides great potential to further our understanding of the mode of action of treatments and to more accurately select which patients will benefit from a particular treatment, serious issues of experimental design must be considered.
We believe that blastocyst transfer is a valuable tool that has enabled IVF programs to more accurately select the embryos with the highest potential for implantation [ 16- 18] allowing for a good pregnancy rate while avoiding high order multiple gestations [ 19, 20].
A community-based observational study confirms the potential of this 70-gene signature to more accurately select breast cancer patients who can forgo adjuvant CHT without compromising outcome.
Conversely, for patients who presented a pCR, the identification of factors predicting the response to treatment and patient outcome may assist the clinician to more accurately select patients who may or may not benefit from such a strategy.
